- Tumor Antigen Reactivity Plays Important Role in TIL Therapy Efficacy
- First-time Production of an Artificial Human Platelet Lysate
- Andelyn’s Platform Used to Manufacture Clinical Grade Viral Vector
- AI Designed DNA Sequences Modulate Cell Differentiation for Gene Therapy Applications
- In Vivo Bioprinting Shows Promise for 3D Printed Implants Without Surgery
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Cellino, Karis Bio Partner on Autologous iPSC-Based Therapy for Cardiovascular Disease
Cellino, a biotechnology firm working on autonomous biomanufacturing for personalized regenerative medicines, has signed a strategic collaboration with Karis Bio, a South Korean cell therapy company, that will allow it to expand into the Asia-Pacific region. The partners aim to industrialize... -
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Attovia Building Immune-Mediated Disease Pipeline with $90M Series C
Attovia Therapeutics CEO Tao Fu Attovia Therapeutics has completed an oversubscribed $90 million Series C financing, which the company plans to use along with existing cash and investments to advance its two lead pipeline candidates through clinical proof-of-concept, as well as expand its... -
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Cyprumed and MSD Agree to Develop Oral Peptide Formulations and CDMO Meribel Pharma Solutions Launches
Cyprumed and MSD signed a nonexclusive license and option agreement to develop oral formulations of MSD’s peptides using Cyprumed’s innovative drug delivery technology. MSD gains nonexclusive global rights to Cyprumed’s oral peptide delivery platform for an undisclosed number of targets. The... -
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Circulating Tumor DNA Test May Help Predict Melanoma Recurrence
A study led by scientists at NYU Langone Health and its Perlmutter Cancer Center has shown that monitoring blood levels of DNA fragments shed by dying tumor cells may accurately predict skin cancer recurrence. The team’s research, involving adult melanoma patients in a Phase III clinical trial... -
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Soil Nitrogen Levels After a Rain
Gardeners claim that nitrogen levels in the soil increase after rain. Water floating down through the air picks up nitrogen and deposits it on and near plants. Lighting adds even more nitrogen to the process. They base their conclusion on the perceived greening of the garden after a rain. In...- Hoca
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Scientists Engineer Bacteria to Produce Sensor Molecules That Can be Detected 90 Meters Away
Bacteria can be engineered to sense a variety of molecules, such as pollutants or soil nutrients. In most cases, however, these signals can only be detected by looking at the cells under a microscope or similarly sensitive lab equipment, making them impractical for large-scale use. Using a new... -
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Lonza Joins Center for Continuous Manufacturing and Advanced Crystallization
Basel-based Lonza joined CMAC, a center for medicines manufacturing research, to enhance its service offering for particle technologies and drug product development and manufacture. Based at the University of Strathclyde in Glasgow, Scotland, CMAC is an international research hub with a... -
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LSD Analog That May Have Potential for Treating Schizophrenia Developed
Psychedelic drugs, such as lysergic acid diethylamide (LSD), can increase neuronal growth, which can have therapeutic effects for conditions such as schizophrenia. However, such drugs can induce hallucinations and may worsen some symptoms. Researchers from the University of California (UC)... -
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Newly Discovered Immune Cell Type Regulates Food Allergies
The gastrointestinal tract is continuously exposed to foreign antigens in food and commensal microbes that have the potential to induce adaptive immune responses for food allergies. In a new study published by Nature titled, “Prdm16-dependent antigen-presenting cells induce tolerance to gut... -
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Autism Symptoms Associated with Gut Microbial Tryptophan Metabolites
Microbiome dysbiosis—changes in the composition of gut microbes that alter the metabolites present—has long been implicated in playing a causative role in the pathophysiology of autism spectrum disorder (ASD). However, the changes in the gut microbial metabolites that are associated with... -
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This Week in Gaming News: April 7th – April 13th, 2025
April is now well and truly underway, and the weather is beginning to “improve” (if, indeed, you’re not one of the contrarians who prefers the rain and the cold, like we are). Whatever the weather happens to be doing outside, though, there’s still plenty of news to talk about if you’re more... -
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Asahi Kasei Establishes Asahi Kasei Life Science to Focus on Bioprocessing
Asahi Kasei has established Asahi Kasei Life Science to operate its bioprocess businesses under a new organizational structure. Through this change, the company can offer the industry more agile and focused services, deeper innovation in bioprocess solutions, and stronger support in emerging... -
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Novel Predictive Algorithm Identifies InDel Signatures Associated with Cancer
Scientists from the University of Cambridge and their collaborators have developed an algorithm that identifies unique patterns caused by insertions and deletions in tumor DNA. Details of the algorithm, which is called PRRDetect, are published in a new Nature Genetics paper titled “A refined... -
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Apathy in Cancer Patients Linked to Brain-Immune Circuit
Cancer takes a devastating toll on the body—but the psychological burden can be just as profound. Many patients, even those with a long history of resilience and optimism, experience notable emotional downturns. New research points to a biological explanation: the lack of motivation and... -
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First Infant Conceived and Born Using Fully Automated Intracytoplasmic Sperm Injection System
Scientists from Conceivable Life Sciences, a biotechnology company, said that the first baby conceived using its fully automated, digitally controlled intracytoplasmic sperm injection (ICSI) system has been born. Full details are available in a new paper in Reproductive Biomedicine Online... -
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Human Cell Maps Uncover Insights in Pediatric Bone Cancer
One of the ultimate goals of biological research is to understand the multiscale organization of the human cell and its relationship to biological function and human disease. As much of cell structure remains uncharted, there has been long-standing interest in developing strategies to map this... -
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Cellares and University of Wisconsin Agree to Automate Clinical-Scale Production of CRISPR-Edited CAR-T
Cellares agreed to collaborate with the University of Wisconsin School of Medicine and Public Health to automate the manufacturing of a CRISPR-edited GD2 CAR-T investigational therapy. Company officials say their Cell ShuttleTM supports early-phase biotechnology and academic cell therapy... -
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Key Neural Pain-Sensing Pathway Recreated in a Lab Dish
Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the brain. Once further processed in the brain, these signals will translate into our subjective... -
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First Potential Treatment Option for MS Found in Drug Tolebrutinib
A Cleveland Clinic-led clinical trial of tolebrutinib, an investigational oral Bruton’s tyrosine kinase inhibitor (a group of drugs originally developed to treat lymphomas and related blood disorders) demonstrated a 31% delay in the onset of six-month confirmed disability progression (CDP) in... -
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Cancer Detection Using Laser-Based Infrared Molecular Fingerprinting Identifies Molecular Patterns
Cancer diagnoses traditionally require invasive or labor-intensive procedures such as tissue biopsies. Researchers at the Ludwig-Maximilians-Universität München (LMU) have now reported on a method that uses pulsed infrared light to identify molecular profiles in blood plasma that could indicate...