- Tumor Antigen Reactivity Plays Important Role in TIL Therapy Efficacy
- First-time Production of an Artificial Human Platelet Lysate
- Andelyn’s Platform Used to Manufacture Clinical Grade Viral Vector
- AI Designed DNA Sequences Modulate Cell Differentiation for Gene Therapy Applications
- In Vivo Bioprinting Shows Promise for 3D Printed Implants Without Surgery
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SAMBAI Selects Akoya’s PhenoCycler-Fusion Spatial Proteomics Technology for Large-Scale Cancer Study
SAMBAI, a team funded through the Cancer Grand Challenges initiative, reported that Akoya Biosciences’ PhenoCycler®-Fusion system will be the foundational spatial proteomics technology used to generate data for a biobank and data repository for cancer equity research. SAMBAI, which stands for... -
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Inhibiting FGFR2 Supports Prevention and Delay of Common Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) is the most prevalent type of pancreatic cancer, characterized as a highly lethal malignancy that is often preceded by precancerous lesions. These lesions are relatively common, but only a small portion will progress to PDAC. In a new study published in... -
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Wacker Biotech Collaborates with RNAV8 Bio on mRNA Therapeutics Development
Wacker Biotech, a CDMO, began a strategic collaboration with Boston-based RNAV8 Bio aimed at progressing the development and production of mRNA-based advanced therapies for the biopharma industry. This new partnership combines Wacker Biotech’s expertise in pDNA/mRNA manufacturing and lipid... -
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Neurodegenerative Disease Treatment Strategy Sparked by Novel DLK Inhibitor
Neurodegenerative conditions such as Parkinson’s disease and Alzheimer’s disease involve progressive neuronal loss due to disease-induced damage. An enzyme known as dual leucine-zipper kinase (DLK) plays a key role in this process, telling neurons that are damaged or unhealthy when they should... -
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Subset of Intestinal Immune Cells Help Suppress Food Allergies in Mice
The intestinal immune system can usually recognize friend from foe. But for approximately 30 million Americans with food allergies—including four million children—immune cells mistakenly identify food as a threat and trigger potentially life-threatening reactions. Now scientists at Washington... -
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Proton-Sensing Mechanism Regulates mRNA for More Therapeutic Options
Since addressing the COVID-19 pandemic, mRNA vaccines have risen as a promising tool for treating a broad range of diseases, such as cancer and genetic disorders. To be effective, foreign mRNA in these vaccines must evade the body’s natural defenses to enter cells and synthesize proteins... -
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Microbial Competition Enhances Oral Vaccine Protection of Gut
An international team of researchers in Zurich and Oxford have identified a promising strategy to combat harmful bacteria in the gut using a combination of oral vaccines and microbiome-based competition. The approach could help eliminate antibiotic-resistant pathogens and reduce dependence on... -
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Organon Acquires Commercialized Biosimilar to ACTEMRA from Biogen
Organon acquired regulatory and commercial rights in the United States for TOFIDENCE, a biosimilar to ACTEMRA®, for intravenous infusion from Biogen. TOFIDENCE, the first approved tocilizumab biosimilar entrant in the U.S. market, was launched in May 2024 and is indicated in certain patients for... -
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Antibiotic Resistance Among Key Bacterial Species Plateaus Over Time
Antibiotic resistance tends to stabilize over time, according to Sonja Lehtinen, PhD, from the University of Lausanne and colleagues. The team published its study, “The evolution of antibiotic resistance in Europe, 1998–2019,” in PLOS Pathogens. Antibiotic resistance is a major public health... -
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StockWatch: Biopharma Funds Tumble with Wall Street as Industry Spared from Worst of Tariffs—for Now
President Donald Trump’s exemption of pharmaceuticals from the “reciprocal” tariffs he announced Wednesday limited the declines of biopharma stocks as financial markets tanked late last week—but the specter of future industry-specific tariffs and import duties still hanging over the industry... -
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Easy seed medallions fine motor craft for kids
I’ve been sharing a number of activities we did to learn about seeds. This seed medallions craft was a fun way to incorporate seeds into an arts and crafts project. It was also a great way to build fine motor skills. Note: For more seed activities your kids will love, see my Botany Unit Study...- Hoca
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Pins in a Bottle: An Activity to Learn about Air Pressure
What’s something that surrounds us all the time but we hardly ever notice or think about it? Air! In fact, air is pressing on us all the time. And ‘air pressure’ is what we call the weight of the air molecules pressing down on everything on earth. This ‘Pins in a Bottle’ activity provides a […]...- Hoca
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Build a 3D rainbow {measurement activity with free printable}
In looking for a rainbow activity to do with my kids, I saw a cute 3D rainbow. I decided to take this idea and turn it into a way for my kids to practice some basic measurement skills. (I also made a printable that I’m sharing here today.) The idea to make a printable was […] The post Build a...- Hoca
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Build a Jack-o-Lantern with this Cute Pumpkin Printable
Carving pumpkins to make jack-o-lanterns is a fun Halloween tradition our family engages in each year. Of course, once the pumpkin is carved, it never lasts more than a day or two before turning into a rotten, moldy mess. So what is a parent to do when their child wants to make jack-o-lanterns...- Hoca
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Printable Halloween Hand Puppets for Kids
These Halloween Hand Puppets came out so cute, I could pinch myself! I put these together one day while my kids were gone, and when they came home they immediately wanted to see what I was working on and give the puppets a try for themselves. Which was lucky for me, as I needed some […] The...- Hoca
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DIY Christmas Cards for Kids to Make
When it comes to kids, I believe the best gift they can give someone at the holidays is a homemade one. So that’s a big part of why I love these DIY Christmas Cards that kids can make to spread some holiday cheer to friends and family. Note: For more awesome Christmas ideas, see my Christmas...- Hoca
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How to Make ‘Spider Web’ Eggs with Kids
Looking for a fun and super simple spider craft you can make with kids? Want to serve some “spooky” eggs for a Halloween treat? Or just looking for a fun snack to munch on that will give kids a giggle? Look no further than these spider web eggs you can make with some very simple […] The post...- Hoca
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Winter Printables Bundle
I’ll be honest and tell you that winter is my least favorite season. The short days, lack of sun, and cold temperatures make me long for spring’s arrival. Nonetheless, there are things to celebrate about winter. Like ice skating, building snowmen, snow ball fights, and drinking hot chocolate...- Hoca
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Do Geraniums Control Japanese Beetles?
A popular claim is that geraniums will paralyze Japanese beetles and keep them away from your other plants. The pest eats the leaves and flowers and a chemical in the plant intoxicates them and they fall to the ground. They then die or birds pick them off, thereby controlling them in your...- Hoca
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Too Much Compost Can Poison Your Garden?
Can you use too much compost? If you believe what you read, compost is the best thing for your garden. If that’s true, how can you have too much? The truth is that too much compost, especially manure and commercial compost, is harmful to your soil and plants. The NPK of Compost NPK Compost is...- Hoca
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