- OxPhos System Evolution Explored, Indicating Links Between Mutations and Disease
- Unlocking the Mystery Behind Barrett’s Esophagus
- STING Inhibition Differences Revealed Between Humans and Mice
- Unnatural Products, Argenx Partner on Macrocyclic Peptides for Immune Disease
- LICORbio Acquires Serva Electrophoresis
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SpearHead Bio Offers Precise Plant Engineering Using CRISPR-Directed Jumping Genes
Keith Slotkin, PhD, first became interested in transposable elements (TE), colloquially known as “jumping genes,” as an undergraduate student. “They just broke all the rules,” he said in an interview with GEN. “They have totally different regulation and inheritance, and they’re highly dynamic.”... -
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Curacao Online Casinos: Top Casinos mit Curacao Lizenz
In Casinos mit Curaçao-Lizenz profitiert ihr von steuerfreien Gewinnen, blitzschnellen Krypto-Auszahlungen und Autoplay ohne Pausen – für ungebremsten Spielspaß ganz ohne deutsche Einschränkungen. Curacao Gaming Authority im Überblick Die Curaçao Gaming Authority beaufsichtigt... -
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Ring Therapeutics Presents Promising New Data on its AnelloBricks Biomanufacturing Platform at ASCGT
Ring Therapeutics presented new data at the ASCGT Conference in New Orleans showing that its AnelloVectors—produced using its AnelloBricks in vitro assembly technology— have successful infectivity and expression of AnelloVectors. The data also demonstrates that the vectors can carry a wider... -
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Protein-Lipid Communication between Intestinal Cells and Gut Microbes Boosts Immunity in Mice
The human gut is home to trillions of microbes that not only aid in digestion but also play a key role in shaping our immune system. These microbes communicate with the body by releasing a range of molecules that influence how immune cells grow and function. To maintain a healthy balance... -
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Forge Biologics Inks AAV Development and cGMP Manufacturing Deal with Fractyl Health
Forge Biologics, a member of the Ajinomoto Bio-Pharma Services group, signed an AAV development and manufacturing agreement to help advance Fractyl Health’s Rejuva* pancreatic gene therapy platform for the treatment of patients with obesity and type 2 diabetes. “We developed our FUEL platform... -
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Tozaro Forms Technical Advisory Board to Boost Smart Polymer Business in Cell/Gene Therapy Bioprocessing
Tozaro, based in Bedford, U.K., formed a technical advisory board (TAB) to provide strategic guidance around commercialization and further development of the company’s smart polymer platform for applications in cell and gene therapy (CGT) chromatography and bio-separation processes. Members of... -
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Sweet Solution: Sugar-Coated Nanotherapy Halts Alzheimer’s Disease by Trapping Toxic Proteins
To combat the progression of neurodegenerative disorders like Alzheimer’s disease and amyotrophic lateral sclerosis, scientists at Northwestern University and their collaborators have developed a method of trapping proteins before they aggregate into toxic structures. Their approach uses a class... -
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Mass Photometry Speeds Up Gene Therapy Manufacturing—No Purification Needed
With multiple FDA-approved treatments and dozens more in clinical trials, gene therapy is rapidly becoming a cornerstone of modern medicine. But as the field matures, the industry faces a growing logistical challenge: how to produce gene therapies at scale, quickly and cost-effectively, without... -
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Working Long Hours May Alter Brain Structure, Study in Healthcare Workers Finds
The findings of preliminary research indicate that long working hours may alter the structure of the brain, particularly those areas associated with emotional regulation and executive function, such as working memory and problem solving. A research team of scientists at Yonsei University... -
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CAR-T Cell Therapy-Related “Brain Fog” Mechanism and Treatment Approaches Identified
After treatment with CAR-T cells—immune cells engineered to attack cancer—patients sometimes tell their doctors they feel like they have “brain fog,” or forgetfulness and difficulty concentrating. A study led by scientists at Stanford School of Medicine has now shown that CAR-T cell... -
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ASGCT 2025: EG 427 Makes Strides in Non-Replicative HSV-1 Vectors for Neurological Therapies
At this year’s annual meeting of the American Society of Gene and Cell Therapy (ASGCT), French biotechnology company EG 427 will share recent advances in the development of its recombinant, non-replicating HSV-1 (nrHSV-1) vector technology. The company plans to present two posters at the... -
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Wolbachia Drives Female Drosophila Promiscuity to Enhance It’s Spread
Some parasites affect their hosts’ behavior. Although the underlying mechanisms remain unclear, one theory is that the change of behavior is to facilitate the spread of the parasite to others in the population. Wolbachia is a parasitic bacterium that infects at least two out of every five insect... -
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Genentech Plans to Invest More than $700 Million in New North Carolina Drug Manufacturing Facility
Genentech plans to invest more than $700 million in a new 700,000-ft2 drug manufacturing facility in Holly Springs, NC. The project is expected to add more than 400 manufacturing jobs when the site is operational and more than 1,500 construction jobs during site development. The new facility... -
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Biopharma Stocks Rise as Trump Orders Drug Price Cuts
Shares of biopharma companies rose after President Donald Trump signed an executive order to lower U.S. prescription drug prices to their levels in other countries, though many details of implementing the “most favored nation” (MFN) pricing policy remain unclear—and one industry group criticized... -
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Test-Time Scaling Improves Speed and Success of AI-Based Antibody Design
G-protein coupled receptors (GPCRs) are the largest protein family encoded by the human genome and represent approximately one-third of all drug targets. However, most GPCR-targeting drugs are small molecules or peptides that struggle with limited selectivity and off-target effects. Nabla Bio... -
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This Week in Gaming News: May 5th – May 11th, 2025
It’s time once again to cast our eyes over the seven days that have just gone by and bring you the highlights when it comes to gaming news. There’s plenty to pore over this week, including a new GTA 6 trailer, Nintendo getting lawsuit-happy again, and the appearance of a beloved Xbox franchise... -
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Can Monarchs Smell Milkweed From 2 Miles Away?
Monarch butterflies and milkweed plants share a special bond. Monarchs rely on milkweed to lay their eggs and feed their caterpillars. For gardeners and conservationists wanting to support these beautiful insects, understanding how Monarchs find milkweed is key. A common claim pops up: Can...- Hoca
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Tumor Antigen Reactivity Plays Important Role in TIL Therapy Efficacy
Scientists from the Moffitt Cancer Center say they now have a better understanding why some lung cancer patients do not benefit from tumor-infiltrating lymphocyte, or TIL therapy. Their findings “Impaired T cell and neoantigen retention in time-serial analysis of metastatic non-small cell lung... -
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First-time Production of an Artificial Human Platelet Lysate
PL BioScience, a German life science company specializing in the production and development of human platelet lysate (HPL) for cell expansion, reported the first-time production of an artificial HPL cell culture solution. In partnership with the Korean biotech DewCell Biotherapeutics, the first... -
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Andelyn’s Platform Used to Manufacture Clinical Grade Viral Vector
CDMO Andelyn Biosciences says that it has manufactured a viral vector with its AAV Curator® Platform for the Nationwide Children’s Hospital’s Cellular Therapy and Cancer Immunology Program. The Adeno-Associated Virus (AAV) will be utilized in a novel cell therapy for Universal-Donor CD38KO...