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    This Week in Gaming News: June 23rd – June 29th, 2025

    Just when we thought the UK had escaped the worst (or best, depending on your perspective) of the hot weather this summer, another heatwave sweeps in and knocks everyone off their sun loungers. Well, the weather outside might be scorching, but we’ve got plenty of fresh gaming news from the week...
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    Thermo Fisher-Tufts Study Links CRO-CDMO Platform to Shorter Cancer Drug Development Timeframe

    Daniel Burch, MD, is a senior vice president leading global biotech solutions for Thermo Fisher’s clinical research and pharma services businesses. Thermo Fisher Scientific’s Accelerator Drug Development solutions, which integrate services for contract development and manufacturing...
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    Severe Epileptic Encephalopathy Linked to Citrate Transporter Mutations

    Citrate is a metabolite essential to the metabolism and development of neurons. A membrane transport protein called SLC13A5 plays a central role in this process and has previously been linked to a particularly severe form of epileptic encephalopathy. Building on data from the recently completed...
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    Vetter Begins Construction of Clinical Manufacturing Site in Illinois

    German CDMO Vetter held an official groundbreaking ceremony for the start of construction on a clinical manufacturing site in Des Plaines, IL. The company has invested approximately $285 million in the new facility. Upstream and ground preparation work on the premises started back in April...
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    Novartis, ProFound Therapeutics Ink Multi-Year Collaboration to Target Cardiovascular Disease Proteins

    Seeking to develop novel medicines for cardiovascular disease, Novartis and ProFound Therapeutics have signed a four-year strategic collaboration. The agreement will allow the partners to combine ProFound’s protein identification capabilities with Novartis’ expertise in cardiovascular drug...
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    Nanozyme-Powered TB Test Enhances Detection for HIV Co-Infection

    When threatened, the bombardier beetle launches a noxious chemical spray by combining two compounds in its abdomen—a natural defense mechanism that doesn’t require external power. It was this beetle’s ingenuity that inspired scientists to tackle one of the deadliest infectious threats today...
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    Mice Regenerate Ear Tissue When Vitamin A Genetic Switch is Flipped

    By flipping an evolutionarily disabled genetic switch involved in vitamin A metabolism, researchers headed by a team at the National Institute of Biological Sciences, Beijing, have enabled ear tissue regeneration in mice. The scientists, co-led by Wei Wang, PhD, and colleagues, performed a...
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    Labviva Automates Chemical Supply Chain for the Life Sciences Industry

    Labviva announced the general availability of Harper Chemical (HarperChem), a new part of its cloud-based inventory management system (IMS). The company debuted HarperChem at this week’s R&D Procurement & Sourcing in Pharma Summit being held at the Hilton Boston Logan Airport. Labviva officials...
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    Tumor Growth Accelerated by Macrophages’ Cytokine Amplification in Drosophila

    By studying what happens when macrophage immune cells encounter dying cancer cells in tumors, scientists at Nagoya University have discovered a mechanism that accelerates tumor growth. When cancer cells begin to die within tumors, they expose signals on their surface that indicate they are...
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    Space Station’s Lab-on-Chip Model Uncovers How Microgravity Drives Muscle Degeneration

    Space exploration activity has been increasing. In turn, researchers are more interested than ever in uncovering more about how space travel affects human health and the progression of disease. Although it is known that microgravity accelerates skeletal muscle degeneration, the effects of space...
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    Solution Building: Merck Avoids One-Size-Fits-All Approach to AI and ML

    Addressing the Goldman Sachs Healthcare C-Suite Unscripted Conference last year, Merck & Co. Chairman and CEO Robert A. Davis told investors the pharma giant was spending undisclosed “significant” capital toward automating processes, analyzing data, and supporting decision-making through AI...
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    Gero’s Structure-Free AI Model Generates Small Molecules from Protein Sequences

    Gero, a biotechnology company developing novel therapeutics for aging and chronic diseases, has released ProtoBind-Diff, a novel masked diffusion language model that generates drug-like molecules for protein targets using only their amino acid sequences. The company has integrated ProtoBind-Diff...
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    Neuron Population Code Underlies Decision Making in the Primate Brain

    When faced with the same evidence, each individual can reach a different decision. How billions of specialized cells make split-second choices has largely been an open research question. In a new study published in Nature titled, “The dynamics and geometry of choice in the premotor cortex,”...
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    SandboxAQ Debuts Public Database of Protein-Ligand Structures and Binding Affinities

    Recently, SandboxAQ launched what it claims is the largest publicly available dataset of protein-ligand pairs with annotated experimental binding potency data. According to the company, the Structurally Augmented IC50 Repository (SAIR) contains about 5.2 million synthetic three-dimensional...
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    Accessing Real-World, Longitudinal Clinicogenomic Data at Scale

    Officials at Velsera say that the company has expanded the capabilities of its Global Data Network (GDN), which they describe as a federated, secure data ecosystem that allows life sciences organizations to access and activate real-world, longitudinal clinicogenomic data at scale. Spanning more...
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    AI-Guided Screen Enhances Beta Cell Transplant Survival

    Can we predict—and prevent—why transplanted beta cells fail? A preclinical study titled “ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation,” from Weill Cornell Medicine, has identified a sex-specific strategy to...
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    Mitochondrial Base Editing Corrects Pathogenic Mitochondrial DNA in Patient-Derived Disease Models

    In a step toward treating mitochondrial diseases, researchers at the University Medical Center Utrecht and their colleagues have used mitochondrial base editing (mtBE) to successfully edit harmful mutations in mitochondrial DNA. Through their newly reported study, the team, headed by Martijn...
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    This Week in Gaming News: June 16th – June 23rd, 2025

    If you’re in the UK, then congratulations on having survived the summer’s first mini-heatwave! We’re sure there will be many more to come before September rolls around. As usual, though, we’re not here to talk about the weather. No, we’re here to recap what’s been happening in the gaming world...
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    LOTTE BIOLOGICS Signs Antibody Manufacturing Contract with Ottimo Pharma

    South Korea-based LOTTE BIOLOGICS signed a contract manufacturing agreement for antibody therapeutics with Ottimo Pharma, a biopharmaceutical company developing PD1/VEGFR2 dual pathway antibodies (Jankistomig) designed to extend the lives of people living with cancer. LOTTE will manufacture...
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    Illumina to Acquire SomaLogic from Standard BioTools

    Illumina announced today it has entered into a definitive agreement with Standard BioTools under which Illumina will acquire SomaLogic, a leader in data-driven proteomics technology, for up to $425 million. Illumina paid SomaLogic $30 million upfront, with the companies later agreeing to an...
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