- OxPhos System Evolution Explored, Indicating Links Between Mutations and Disease
- Unlocking the Mystery Behind Barrett’s Esophagus
- STING Inhibition Differences Revealed Between Humans and Mice
- Unnatural Products, Argenx Partner on Macrocyclic Peptides for Immune Disease
- LICORbio Acquires Serva Electrophoresis
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Million Species Listing: Basecamp Research Unearths Trove of Sequence Data From Novel Species
In the latest step to tackle biology’s data scaling law, Basecamp Research has announced BaseData, the largest database for sequence-based model training, composed of 9.8 billion new protein sequences and one million newly discovered species. The company-generated dataset offers a 10-fold... -
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Smelling Food Activates Neurons That Curb Appetite in Lean Mice
Scientists at the Max Planck Institute for Metabolism Research have identified a network of nerve cells that may be responsible for a reduction in feelings of hunger that may be felt as a result of smelling food, in mice. The team discovered a direct connection from the nose to a group of nerve... -
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Shedding Light on AMR Superbugs: From Penicillin to Photoactivated Precision
In 1928, Alexander Fleming’s accidental discovery of penicillin revolutionized medicine, turning once-deadly infections into curable inconveniences. But nearly a century later, that miracle is unraveling. As antibiotic resistance (AMR) spreads, the microbes are striking back—stronger, smarter... -
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Cytiva Completes $1.6 billion in Strategic Investments to Further Enhance Global Supply Chain
Officials at Cytiva report that the company has completed significant expansion projects in several locations in the U.S., Europe, and Asia as part of its ongoing commitment to customers developing and manufacturing advanced therapeutics. Set to continue through 2028, these expansions will meet... -
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Biological Aging Markers Elevated in Pediatric Multiple Sclerosis Cases
Children living with multiple sclerosis (MS) show signs of accelerated biological aging, even in their teenage years. This is according to new research from scientists at the University of California (UC), San Diego, and their collaborators that was published recently in a Neurology paper titled... -
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University of Oxford and ReciBioPharm Expand Malaria Vaccine Collaboration
The University of Oxford and ReciBioPharm, Recipharm’s advanced biologics division and a CDMO, report that they are expanding their long-standing collaboration with the development of two blood-stage malaria vaccine candidates for Phase I/II clinical trials. Since 2016, this collaboration has... -
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AI Tool Uncovers Gene Combinations Underlying Genotype–Phenotype Relationships in Complex Traits
Northwestern University biophysicists have developed a new computational tool for identifying gene combinations underlying complex illnesses such as diabetes, cancer, and asthma. Unlike single-gene disorders, complex conditions are influenced by a network of multiple genes, which means there is... -
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Inspired by Viral Spike Proteins, Multimeric Aptamers Target Protein Complexes with Precision
Synthetic and inexpensive to produce, aptamers are attractive alternatives to antibodies for biomedical diagnostics and therapeutics. When new aptamer binders are needed, for example, to detect a new virus, they are developed from libraries of millions of nucleic acid sequences. Until now, such... -
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Recursion Eliminating 20% of Workforce, Citing Pipeline Pruning and Capital Markets
Recursion said today it is eliminating approximately 20% of its workforce—about 160 jobs—in a restructuring the AI-based drug developer said reflects both its recently-pruned pipeline and the challenge of securing financing seen across the biopharma industry. Salt Lake City-based Recursion... -
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Biomanufacturing Gains as Lab Leasing Lags
The U.S. life sciences real estate sector is experiencing some turbulence in 2025, as business uncertainty contributed to a sharp drop-off in demand in Q1. But a notable uptick in pharma companies announcing U.S. investments could lead to a boom in domestic biomanufacturing, according to JLL’s... -
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Scalable CRISPR-Based Gene Editing Improves Tomato Crop Traits
In a study published in Nature Communications titled “Construction of multi-targeted CRISPR libraries in tomato to overcome functional redundancy at genome-scale level,” researchers from Tel Aviv University have developed a genetic editing method tailored to crop plants to influence various... -
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Scientists Urge NIH Director to Restore Research Grants Halted by Trump Administration
Over 1,200 NIH scientists signed a letter sent to Director Jay Bhattacharya MD, PhD, saying that they collectively dissent on Trump administration “policies that undermine the NIH mission, waste public resources, and harm the health of Americans and people across the globe.” The researchers... -
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This Week in Gaming News: June 2nd – June 8th, 2025
It’s summer show season in the gaming world, and so you can expect a slew of new announcements and updates on existing games this week. Regardless of the year, it’s never difficult to find someone who says shows from the likes of Xbox, PlayStation, and Devolver Digital were disappointing, but we... -
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T-Cell Response to mRNA Vaccine Improved with Cytokine Adjuvant
Lipid nanoparticle (LNP) mRNA vaccines induce robust immune responses and provide protection against infectious diseases. However, this immunity can be short-lived, resulting in the need for frequent booster vaccinations. In a new study published in Science Immunology titled, “An Il12 mRNA-LNP... -
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Novel Biofabrication Technique Could Advance Bioprinting and Tissue Engineering
Researchers from the Renaissance School of Medicine at Stony Brook University say they have developed a new method of bioprinting physiological materials. Called TRACE (Tunable Rapid Assembly of Collagenous Elements), the technique addresses long-standing challenges in bioprinting natural body... -
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Beach Reads for the Biologist Bookworm
When the weather warms up and the school year comes to an end, many of us add ordering a new swimsuit and buying sunscreen to the to-do list. One of my favorite summer chores is finding a new book to take from the beach to the pool. Here, we present a list of the books some of GEN‘s editors... -
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StockWatch: Report of $3B+ Merck Buyout Offer Propels MoonLake Stock Surge
Speaking on the company’s first-quarter earnings call in April, Merck & Co. [NYSE: MRK] chairman and CEO Robert M. Davis sought to reassure analysts that the company was very much interested in growing through mergers and acquisitions (M&A) despite an uncertain economic climate that has dampened... -
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HSV-1 Encephalitis Prevented by Treatment Targeting Viral Enzymes
If you have ever experienced a cold sore, you may be one of the estimated 3.8 billion people worldwide (64%) who are infected with herpes simplex virus type 1 (HSV-1). Though the majority of people experience no or mild symptoms, HSV-1 has the ability to cause a rare, life-threatening... -
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AAV Gene Therapy Eases Alzheimer’s Symptoms in Mice
Scientists from the University of California, San Diego (UC San Diego), have published data from a study that tested the effects of a gene therapy for Alzheimer’s disease (AD) dubbed AAV9-Synapsin-promoted Cav-1 (SynCav1) in mice. The results indicate that the therapy could be an effective way... -
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Boltz-2 Released to Democratize AI Molecular Modeling for Drug Discovery
Researchers from the Massachusetts Institute of Technology (MIT) Jameel Clinic for Machine Learning in Health have announced the open-source release of Boltz-2, which now predicts molecular binding affinity at newfound speed and accuracy to democratize commercial drug discovery. The model is...