- OxPhos System Evolution Explored, Indicating Links Between Mutations and Disease
- Unlocking the Mystery Behind Barrett’s Esophagus
- STING Inhibition Differences Revealed Between Humans and Mice
- Unnatural Products, Argenx Partner on Macrocyclic Peptides for Immune Disease
- LICORbio Acquires Serva Electrophoresis
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Rapid Method for Cell Density Measurement Could Help Predict Tumor Response to Treatment
Measuring the density of a cell can reveal a great deal about the cell’s state. As cells proliferate, differentiate, or undergo cell death, they may gain or lose water and other molecules, which is revealed by changes in density. Tracking these tiny changes in cells’ physical state is difficult... -
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CellProthera Selects CELLforCURE by SEQENS for Phase III GMP Manufacturing
France-based CellProthera chose CELLforCURE by SEQENS as its CDMO partner for a planned Phase III trial. The trial will evaluate ProtheraCytes®, an autologous expanded CD34+ stem cell-based therapy aimed at improving heart failure event-free survival following a severe heart attack. CellProthera... -
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The News from New Orleans: GEN‘s Takeaways from ASGCT
Kevin Davies, PhD, editorial director and Julianna LeMieux, PhD, deputy editor in chief at GEN have been on the ground of the ASGCT meeting for a few days—in the talks, expo hall, and press room, covering as much of the news as they can. In this video, filmed from the conference floor, Kevin and... -
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Donor Heart Damage from Cold Storage May Be Prevented by Diuretic
Researchers headed by teams at Michigan Medicine and Mayo Clinic have discovered how a molecular process that occurs when donor hearts are preserved in cold storage contributes to failure after transplant. In the study, in both humans and animals, researchers found that a drug already used to... -
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Jungle Bounce – Bounce Your Way Through the Jungle!?
Jungle Bounce – Bounce Your Way Through the Jungle! Game Overview Jungle Bounce is an exciting, fast-paced arcade game set in a lush jungle environment. Navigate your bouncy character through an increasingly challenging obstacle course of bamboo stalks and tree trunks. As you progress, the... -
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Regeneron to Acquire 23andMe with Winning $256M Bid
More than two months after filing for Chapter 11, 23andMe has found a buyer in Regeneron Pharmaceuticals, which has agreed to acquire substantially all the bankrupt direct-to-consumer genetic testing pioneer’s assets for approximately $256 million after winning a competitive auction on Friday... -
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Prime Medicine Chops 25% of Workforce, Pivots Pipeline as CEO Quits
Keith Gottesdiener, MD, former president and CEO of Prime Medicine Prime Medicine is eliminating 25% of its workforce—about 50 jobs—in a restructuring that includes the company pivoting its prime editing-based pipeline focus to liver disease and programs funded by external collaboration... -
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This Week in Gaming News: May 12th – May 18th, 2025
It’s time once again for us to take a look at the week that’s just gone by in the gaming world, and we’re smack bang in the middle of financials season, so expect plenty of numbers. That’s not to say other things aren’t going on, of course; just that many studios are choosing now to [...] The... -
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StockWatch: With Inozyme Buyout, BioMarin Pursues Growth via M&A
For years, market watchers have speculated about some biopharma giant or other buying out BioMarin Pharmaceutical (NASDAQ: BMRN), which is why the rare disease drug developer has appeared in every GEN A-List of Top 10 Takeover Targets, from 2013 through the latest list in February 2025. This... -
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Illumina Sues Element Biosciences, Alleging Infringement of Flow Cell, Imaging Patents
Illumina is suing Element Biosciences, with the sequencing giant accusing its smaller rival of infringing on five of its patents covering flow cell and imaging technologies used in automated genetic sequencing, and Element vowing to defend itself in court. In a complaint filed Thursday in U.S... -
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EvoCAST Harnesses CRISPR-Linked Bacterial Transposes to Insert Genes Into Human Cells
Using laboratory-evolved versions of CRISPR-associated transposes (CASTs) from bacteria, scientists at the Broad Institute and Columbia University were able to insert healthy genes into human cells efficiently enough for potential therapeutic applications. Full details about the system, dubbed... -
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10x Settles Bruker, Vizgen Patent Lawsuits
10x Genomics has settled patent infringement lawsuits with a pair of rivals, Bruker and Vizgen, through settlements that could reshape competition within the emerging single-cell and spatial genomics fields. On Wednesday of last week, Bruker said it became the second rival to settle with 10x in... -
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3PBIOVIAN Introduces Two Platforms for AAV and pDNA Manufacturing
CDMO 3PBIOVIAN officials report that the company has launched the AAVion® platform, a fully integrated adeno-associated virus (AAV) manufacturing solution designed to accelerate gene therapy development. They add that the platform, built around a proprietary HEK293 cell line, unifies the steps... -
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Malaria Turns Down Genes to Evade Immunity, Enable Chronic Infection
Researchers at Weill Cornell Medicine have discovered how Plasmodium falciparum, the parasite that causes malaria when transmitted through a mosquito bite, can hide from the body’s immune system, sometimes for years. The team’s preclinical study showed that the parasite can shut down a key set... -
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Biotech and Beignets: The News from Day One of ASGCT
The American Society of Gene and Cell Therapy (ASGCT) meeting is off and running in New Orleans! Kevin Davies, PhD, editorial director and Julianna LeMieux, PhD, deputy editor in chief at GEN are on the ground—in the talks, expo hall, and press room, covering as much of the news as they can... -
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Immune Cell Type Linked to Oral Tolerance and Childhood Food Allergies
A decade ago, a clinical trial in the U.K. notably showed that children who were exposed to peanuts in the early months of life had reduced risk of developing a peanut allergy compared with children who avoided peanuts. Now, a study by researchers at Memorial Sloan Kettering Cancer Center (MSK)... -
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New Multi-Species Bat Organoid Platform Enhances Pandemic Preparedness
The world’s largest bat organoid platform, which promises improvement in the study of zoonotic viruses, has been newly developed by scientists at the Institute for Basic Science (IBS) in Korea. By modeling virus-host interactions in a biologically relevant way, the platform allows scientists to... -
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10x Eliminates 8% of Workforce in $50M Cost-Cutting Effort
10x Genomics says it eliminated 8% of its workforce—about 100 jobs—as part of a company effort to cut $50 million in costs and better reflect strategic priorities that include addressing the uncertain financial climate raised by federal cuts in research funding to its majority of customers in... -
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Estrogen-Related Receptors Boost Muscle Mitochondria in Mice
We all learned in high school biology that mitochondria are the powerhouse of the cell. But powering up those cellular engines requires a molecular spark. Now, scientists at the Salk Institute have pinpointed a set of transcription factors—estrogen-related receptors (ERRs)—as essential... -
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Imprint Labs Launches to Pioneer “Forensic Immunology” For Chronic Disease
Beck Brachman, PhD, knew the immune system was somehow involved in depression. “If you transfer immune cells from stressed and ‘depressed’ mice to new mice, will that cause depressive symptoms? Will they be anxious?” she posed while recalling her earliest work in preventative psychopharmacology...